Corticosteroid를 이용한 하악에 발현된 Langerhans Cell Histiocytosis의 치료
Use of corticosteroids in the treatment of Localized Langerhans cell histiocytosis of the mandible
최정용, 이상화, 윤현중,
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최정용 ( Choi Jung-Yong ) - 가톨릭대학교 의과대학 성모병원 구강악안면외과
이상화 ( Lee Sang-Hwa ) - 가톨릭대학교 성모병원 치과 구강악안면외과
윤현중 ( Yoon Hyun-Joong ) - 가톨릭대학교 의과대학 성모병원 구강악안면외과
KMID : 0360120090310030249
Abstract
Langerhans cell histiocytosis(LCH), previously known as histiocytosis X, is rare, proliferative disorder in which the accumulation of pathologic Langerhans cell leads to tissue infiltration and destruction. The jaw is involved 10~20% of all LCH and most common oral symptoms are jaw swelling or a palpation mass. Most of subjects are males and disease appears to start before the age of 10 years. An 11 years old girl was referred from pediatric department. Histological examination confirmed the diagnosis LCH. She was treated intra-lesional injection of corticosteroid. The overall outcome was excellent. After a follow-up period of 20 month, the patient present with no evidence of residual disease on Panoramic view and whole body bone scan. We report this early recognized LCH case treated by corticoid injection in good progress with literature review.
키워드
Langerhans cell histiocytosis;Eosinophilic granuloma;Corticosteroids;Intralesional injection
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